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Conduritol B epoxide treatment of 4L
a new class of potential cancer therapeutics
Ambrisentan 1267 CC(C)C1C=CC(OCC(=O)NC2CC(C)(C)NC(C)(C)C2)=C(Br)C=1Ambrisentan, also known as BSF 208075 and LU 208075, is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6 minute walk distance) compared with placebo in two double blind, multicenter trials (ARIES 1 and ARIES 2). Ambrisentan was approved by